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Other Penn/NBIC Facilities

Instrumentation has been modified or custom designed in order to accommodate the most recent innovations in local measurement probes

Discher Labs

Digital Instruments Multimode + Nanoscope III AFM
Asylum MFP-1D
Asylum MFP-3D
Micropipette Aspirator
HPLC / Fraction collector

  • Contact + intermittent contact AFM
  • Force measurements
  • Variable-Temp AFM
  • Fluorescence + optical microscopy
  • Total internal reflection + AFM
  • Polymer synthesis
  • “Cysteine shotgun” analysis

Slideshow with additional information

  Discher Labs
Chemistry Facilities

Mass Spectrometry
Nuclear Magnetic Resonance Facility
2D laser facilities
Wide-field Video Microscopy
Center for Molecular Modeling
Glass Shop

  • Single molecule or particle tracking
  • protein conformational dynamics
  • Real-time single molecule and single
  • particle tracking
  • Time-lapse fluorescence measurements
  • Single molec. wide-?eld imaging in vivo

Slideshow with additional information

  Chemistry Facilities
Bau Lab

Upright Olympus BX51 Microscope
Inverted Olympus IX71 Microscope
Eppendorf TransferMan NK Micromanipulator
Narishige Hydraulic Micromanipulator
HEKA double patch clamp EPC 10 amplifer

  • Optical (fluorescent) microscopy
  • Electrochemistry and electrophysiology
  • Anodic bonding
  • Thermal bonding press
Goldman Lab

Single Molecule Polarization TIRF Microscopy
Single Molecule TIRF/TRAP/FRET Microscopy
Single Molecule TIRF/FRET Microscopy

  • Single Molecule pol-TIRF assay
  • 3D tracking of single motor proteins
  • Low background Fluorescence imaging using TIRF
  • Localizing a Fluorophore with on nanometer precision
  • Manipulating single particle with sub-pN force using optical trap
  • Monitoring confomational / distance change with sub-nm with FRET

Slideshow with additional information

  Goldman Lab
Johnson Lab

Nanotube Furnaces
e-Beam Lithography
Optical Lithography
Vapor Sensing Testbed

  • Nanotube and graphene deposition
  • TEM + in situ electronic measurements
  • Hybrid AFM (scanned gate and electrostatic force)
  • Bio-functionalization

Slideshow with additional information

  Johnson Lab
Drndić Lab

Electrical transport with fA resolution from 4 K to 650 K with optical excitation
Wire bonder
Table mounted lasers
Fluorescence microscope
Atomic force microscope

  • Nanopores
  • Transmission electron mircoscopy
  • Silicon nitride membrane fabrication
  • Lithography
  • Atomic later deposition

Slideshow with additional information

  Drndić Lab



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