Nano-scale Structures and Forces
Andre Brown, Prashant Purohit, Irena Ivanova, Amnon Buxboim, Joe Swift, Dennis Discher
Stopping Blood Flow at ‘Wound’ Interfaces is a central Mechanical Task of Fibrin clots, but the Molecular Basis for Fibrin resilience is not known. We demonstrate forced unfolding.
Cells adhere to Matrix Proteins such as Collagen, which is the most abundant protein in animals, but collagen is often Crosslinked. We want to understand the effects of that crosslinking.