NUGGET
A Novel Method for Investigating the Azimuthal Rotation of Molecular Motors Utilizing Dielectrophoresis and Optical Tweezers
Mark E. Arsenault, Haim H. Bau, and Yale E. Goldman
The left-handed corkscrew motion of a myosin X-coated bead as it travels along an actin filament
Objectives:
Facilitate the unhindered motion of protein motors and observe their trajectories
- We have developed a technique to study the motion of molecular motors along filaments
- The 3D-positions of myosin V and myosin X-coated beads were tracked with custom-written software
- Both myosin V and myosin X-coated beads follow a left-handed spiraling path around the suspended actin filaments