square logo


navigation:  << previous  ||  next >>

Block Copolymer Nanotemplates for Aligning Actin Filaments

R. J. Composto (SEAS) and Y. Goldman (SOM) The University of Pennsylvania

image 1


This collaboration aims to organize block copolymers as templates for F-actin organization. We have evaluated several amphiphilic diblock copolymers that self-assemble into spherical domains at a length scale that is commensurate with biopolymer size and remain stable during F-actin attachment in buffer. As described below, a new method is demonstrated to stabilize nanoscale domains and covert them to positive charge to become discrete attachment points for F-actin adsorption.



Nano/Bio Interface Center @ The University of Pennsylvania
Home | Participents | Research | Education | Industry | Partners | Publications | Facilities | Events | Calendar | NIRT | Members