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Molecular Machines in Living Cells


P. Nelson

It is now possible to track the directed motion of organelles in living cells with nanometer accuracy, for example labeled peroxisomes (A, inset) in a long cellular protrusion (right). The resulting time series (B) reveal that intracellular transport is highly coordinated. The continuous wavelet transform of in vivo tracked vesicle traces reveals surprising symmetries and self-similarities (C).

A,B courtesy of Paul Selvin (UIUC); C by Igor Kulic (Penn NBIC).



Nano/Bio Interface Center @ The University of Pennsylvania
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